Personal Care & Cosmetics

Intensilk™

Provital

Intensilk™, the first cosmetic active proven to mimic caloric restriction in adipocytes, opens a new path in body well-aging. Derived from locally sourced apple blossom, Intensilk™ remasters longevity science to dermohack the body, delivering an intensive anti-cellulite remodeling solution that acts on both fat reduction and tissue architecture to smooth cellulite dimples, restore firmness, and improve skin texture. A multiomic analysis reveals Intensilk™’s ability to reprogram adipocyte metabolism from lipid storage to energy recycling by triggering caloric restriction pathways (PI3K–Akt–mTOR modulation) and activating lipophagy, while reducing inflammation and remodeling dermal and hypo-dermal extracellular matrix.